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This information is for healthcare professionals only.

Information for health and care professionals

Site Close-out

The PRINCIPLE Trial has now closed recruitment. Thank you to all of the participating GP sites who helped to recruit and follow-up with many of the PRINCIPLE participants. 

If you are a green-lit site, we will be contacting you about a formal site-close that we will be conducting remotely. Please click this link to download the zipped folder of the Investigator Site File. 

Click here to download: Investigator Site File. 

Thank you for participating  in  COVID-19 research! 

These resources aim to support all health professionals working with or interested in the PRINCIPLE Trial.

Resources are divided according to medical centre type, including GP surgeries, secondary care, care homes, NHS Trusts, and 111 Hubs.

Please navigate to where best suits your health care centre type. If you have any questions about this please feel free to contact the PRINCIPLE Trial team - principle@phc.ox.ac.uk

Newsletters:

Trial Newsletter 23 July 2021

913 KB, PDF document

Trial Newsletter 08 July 2021

863 KB, PDF document

Trial Newsletter 18 June 2021

1 MB, PDF document

Trial Newsletter 28 May 2021

1 MB, PDF document

Trial Newsletter 14 May 2021

932 KB, PDF document

Trial Newsletter 23 Apr 2021

753 KB, PDF document

Letters:

The Chief Medical Officers of England, Wales, Scotland and Northern Ireland, and the NHS Medical Director, have written to all doctors strongly encouraging participation in the national randomised trials in COVID-19, of which PRINCIPLE is one. 

Open letter: The importance of COVID-19 clinical trials
Open letter: Recruiting patients for clinical trials for COVID-19 therapeutics