The PRINCIPLE Trial is now Closed.
A massive thank you to all our participants and colleagues for their contribution to this incredible research. YOUR INTEREST IN THE PRINCIPLE TRIAL IS GREATLY VALUED.
We will continue to update our website with any news or publications from this study. If you have any questions please contact us.
PRINCIPLE: Helping to find treatments for COVID-19 from home
PRINCIPLE is a UK-wide clinical study from the University of Oxford to find COVID-19 treatments for recovery at home.
We are looking for medicines that can help people with COVID-19 symptoms get better quickly and stop them needing to go to hospital. PRINCIPLE recruited participants through this website and also through GP practices across the UK.
PRINCIPLE was open to all with ongoing symptoms of COVID-19, regardless of vaccination status.
Results and Publications:
PRINCIPLE has already made some important findings on the effectiveness of COVID-19 treatments. If you would like to find out more about the some of the results and findings so far from PRINCIPLE please use the link below.
Community outreach and partnerships:
The PRINCIPLE team have partnered with a wide range of community groups and organisations across the UK to help raise awareness and increase inclusivity in the trial. To find out more about this work or see some of our translation resources please use the link below.