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Latest research news and updates

Favipiravir to be investigated as a possible COVID-19 treatment for at-home recovery in the PRINCIPLE trial

Could the antiviral favipiravir help transform COVID-19 into an illness that can be successfully treated by general practitioners?

PRINCIPLE COVID-19 treatments trial widens to under 50s and adds colchicine

From today, the UK’s national priority platform trial of COVID-19 treatments for recovery at home launches its investigation of the gout drug colchicine, and expands for the first time to include adults of any age.

Azithromycin and doxycycline are not generally effective against COVID-19 in patients treated at home, shows PRINCIPLE trial

Update from the Chief Investigators of the Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE), 25 January 2021

De Montford University Leicester students to support PRINCIPLE trial recruitment

Students from De Montfort University Leicester (DMU) are the first in the country to help drive the PRINCIPLE clinical study to find Covid-19 treatments for the over 50’s that can help speed up recovery.

Inhaled corticosteroids to be investigated as a possible treatment for Covid-19 in national PRINCIPLE Trial

Inhaled budesonide is an inexpensive, safe and commonly prescribed treatment for asthma and COPD. It is the fourth medication to be tested in PRINCIPLE.

Two major pharmacy chains join PRINCIPLE Trial

Two of the UK’s largest pharmacy chains, LloydsPharmacy and Well Pharmacy, are tasking their branches with helping to find suitable patients for the PRINCIPLE Trial of Covid-19 treatments.

Britain’s most influential Hindu temple spreads awareness of the PRINCIPLE trial among Indian community

Europe’s BAPS Swaminarayan Sanstha, the largest Hindu temple outside of India, is supporting their community during the coronavirus pandemic by spreading awareness of the PRINCIPLE trial of Covid-19 treatments.

PRINCIPLE Trial of COVID-19 treatments recruits 1000th participant

More than 1000 people across the UK have signed-up to take part in the UK-wide PRINCIPLE Trial of potential community-based treatments for COVID-19, led by Oxford University.

PRINCIPLE Trial to strengthen Black, Asian and minority ethnic community participation

Professor Mahendra G Patel, University of Bradford, joins PRINCIPLE Trial as National Black, Asian and minority ethnic Community and Pharmacy Lead

PRINCIPLE and ZOE partner to widen access to trial

Oxford University and the COVID Symptom Study app are joining forces to widen access to the PRINCIPLE trial of potential treatments for COVID-19.

PRINCIPLE Trial calls on UK primary care to support patient recruitment

The Co-Chief Investigators of the PRINCIPLE Trial, Professor Chris Butler and Professor Richard Hobbs, write an open letter to health professionals across UK primary care calling on their support, so those who are still contracting COVID-19 are given the opportunity to join the trial.

National priority COVID-19 trial recruits first patients

Researchers from Oxford University are now enrolling participants into PRINCIPLE, the first clinical trial of potential COVID-19 treatments to take place in GP practices.

GP practices urged to join COVID-19 research

The Nuffield Department of Primary Care Health Sciences at the University of Oxford and the Royal College of General Practitioners (RCGP) have joined forces with clinical system supplier EMIS Health to urgently recruit as many GP practices as possible for COVID-19 research.