The PRINCIPLE Trial has now closed recruitment. Thank you to all of the participating GP sites who helped to recruit and follow-up with many of the PRINCIPLE participants. 

If you are a green-lit site, we will be contacting you about a formal site-close that we will be conducting remotely. Please click this link to download the zipped folder of the Investigator Site File. 

Thank you for participating  in  COVID-19 research! 

OneDrive:  Investigator Site File

Please find included the documents and check list for sites that were Recuiter Sites on the PRINCIPLE Trial. If your site was a Fully Green Lit Site please see the list below.

If your site was a Recuiter Site please follow through the Site Closure Check list and find any necessary documents below. 

If you have any queries about this process, please feel free to contact the PRINCIPLE team at 0800 138 0880 or email us at principle@phc.ox.ac.uk.

• Site Closure Checklist - Recuiter Sites
• Hydroxychloroquine Accountability Log
• Medication Destruction Log

Please find included the documents and check list for sites that were Green Lit Sites on the PRINCIPLE Trial.

If your site was not provided a Greenlight Email by the PRINCIPLE trial team and has not completed the Greenlight process, it is likely you are a Recruiter Site and should please see the list above.

If your site was a  Green Lit Site please follow through the Site Closure Check list and find any necessary documents below. 

If you have any queries about this process, please feel free to contact the PRINCIPLE team at 0800 138 0880 or email us at principle@phc.ox.ac.uk.

• Close-out Checklist - Green Light Sites
• Delegation Log 
• Training Log
• Hydroxychloroquine Accountability Log
• PRINCIPLE Medication Destruction Log